Lgals8 (NM_018886) Mouse Recombinant Protein
产品名称: Lgals8 (NM_018886) Mouse Recombinant Protein
英文名称: Lgals8 (NM_018886) Mouse Recombinant Protein
产品编号: PM47343M5
产品价格: 0
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: null
安诺伦(北京)生物科技有限公司
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产品概述:Purified recombinant protein of Mouse lectin, galactose binding, soluble 8 (Lgals8), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug 蛋白长度:A DNA sequence from Mouse cDNA ORF Clone, [GM34175V], encoding Mouse full-length Lgals8. 表达系统:HEK293T 种属:Mouse 标签类型:C-MYC/DDK 分子量:36.6 kDa 通用名:Lgals8 总结:Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.[UniProtKB/Swiss-Prot Function] 形式:Liquid 浓度:>50 ug/mL as determined by microplate BCA method 纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. 别名:1200015E08Rik; AI326142; D13Ertd524e; Lgals-8