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Anti-MMP-2 Monoclonal Antibody
产品名称: Anti-MMP-2 Monoclonal Antibody
英文名称: Anti-MMP-2 Monoclonal Antibody
产品编号: K001437M
产品价格: null
产品产地: 北京
品牌商标: solarbio
更新时间: 2025-02-11T13:09:55
使用范围: WB IF
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
Anti-MMP-2 Monoclonal Antibody
品牌:solarbio | 货号:K001437M
英文名称 | Anti-MMP-2 Monoclonal Antibody |
---|---|
别名 | CLG4;CLG4A;MMP-2;MMP-II;MONA;TBE-1 |
应用 | WB IF |
稀释比例 | WB 1:1000. |
交叉反应 | Transfected Rat Human |
蛋白分子量 | 72kDa |
Gene ID | 4313 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG1 |
免疫原 | Purified recombinant human MMP-2 protein expressed in E.coli. |
性状 | 液体 |
Public Immunogen Range | Purified recombinant human MMP-2 protein expressed in E.coli. |
Subcellular Locations | Cytoplasm Membrane Mitochondrion Nucleus Secreted extracellular matrix extracellular space |
Swiss Prot | P08253 |
克隆号 | 3A8-C1-E8 |
克隆类型 | Monoclonal Antibody |
背景资料 | This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. |