Anti-MMP-2 Monoclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
Anti-MMP-2 Monoclonal Antibody

Anti-MMP-2 Monoclonal Antibody

商家询价

产品名称: Anti-MMP-2 Monoclonal Antibody

英文名称: Anti-MMP-2 Monoclonal Antibody

产品编号: K001437M

产品价格: null

产品产地: 北京

品牌商标: solarbio

更新时间: 2025-02-11T13:09:55

使用范围: WB IF

北京索莱宝科技有限公司
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Anti-MMP-2 Monoclonal Antibody

品牌:solarbio | 货号:K001437M
商品货号:商品品牌:规格基本售价:选择规格
K001437M-50ulsolarbio50ul960.00元
K001437M-100ulsolarbio100ul1600.00元
英文名称Anti-MMP-2 Monoclonal Antibody
别名CLG4;CLG4A;MMP-2;MMP-II;MONA;TBE-1
应用WB IF
稀释比例WB 1:1000.
交叉反应Transfected Rat Human
蛋白分子量72kDa
Gene ID4313
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG1
免疫原Purified recombinant human MMP-2 protein expressed in E.coli.
性状液体
Public Immunogen RangePurified recombinant human MMP-2 protein expressed in E.coli.
Subcellular LocationsCytoplasm Membrane Mitochondrion Nucleus Secreted extracellular matrix extracellular space
Swiss ProtP08253
克隆号3A8-C1-E8
克隆类型Monoclonal Antibody
背景资料This gene is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. The protein encoded by this gene is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.