产品概述：Purified recombinant protein of Human cortistatin (CORT), full length, with N-terminal HIS tag, expressed in E. coli, 50ug

蛋白长度：A DNA sequence encoding human full-length CORT

表达系统：E. coli

种属：Human

标签类型：N-His

分子量：17 kDa

通用名：CORT

总结：This gene encodes a neuropeptide that is structurally similar to somatostatin. It binds to all known somatostatin receptors, and shares many pharmacological and functional properties with somatostatin, including the depression of neuronal activity. However, it also has many properties distinct from somatostatin, such as induction of slow-wave sleep, apparently by antagonism of the excitatory effects of acetylcholine on the cortex, reduction of locomotor activity, and activation of cation selective currents not responsive to somatostatin. The preproprotein undergoes further processing into multiple mature products. Read-through transcripts exist between this gene and the upstream APITD1 (apoptosis-inducing, TAF9-like domain 1) gene, as represented in GeneID:100526739. [provided by RefSeq, Nov 2010]

形式：Liquid

浓度：>50 ug/mL as determined by microplate BCA method

纯度：> 80% as determined by SDS-PAGE and Coomassie blue staining

储存溶液：25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl.

别名：CST-14; CST-17; CST-29; SST2